Quality of Life There is a strong connection between your physical function and quality of life. Generally, the better you can move and the longer you can preserve physical function, the more independence you can maintain over everyday activities. In fact, even if two people have the exact same score, they could still be experiencing drastically different symptoms. This is because symptoms affect different regions of the body and can vary from person to person.
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The ALSFRS-R measures 12 aspects of physical function categorized within 4 functional domains bulbar, fine motor, gross motor, and respiratory. Each aspect of function is scored from 4 normal to 0 no ability. The maximum total score is 48, and the minimum total score is 0. Two patients with similar overall scores can still exhibit very different symptoms. New considerations in the design of clinical trials for amyotrophic lateral sclerosis. Clin Investig Lond. J Neurol Sci.
The heterogeneity of amyotrophic lateral sclerosis: a possible explanation of treatment failure. Curr Med Chem. Amyotrophic lateral sclerosis: a consensus viewpoint on designing and implementing a clinical trial. Swash M. New ideas on the ALS functional rating scale. J Neurol Neurosurg Psychiatry. Quantifying disease progression in amyotrophic lateral sclerosis.
Ann Neurol. Amyotrophic lateral sclerosis ALS fact sheet. National Institute of Neurological Disorders and Stroke website. Published June Accessed April 13, Eisen A. Motor neurone disease. Landmark Papers in Neurology. The American Academy of Neurology. The care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies. Accessed May 1, Amyotroph Lateral Scler. Follow Us:.
Amyotrophic Lateral Sclerosis Functional Rating Scale
Assessing ALS Function